Cell-derived micro-environment helps dental pulp stem cells promote dental pulp regeneration

Pulp Regeneration by Harnessing Dental Pulp Stem Cells

Stem Cells of the Dental Pulp

 Dental Pulp Stem Cells (DPSCs) can be found within the cell rich zone of dental pulp. These stem cells, under specific stimuli, differentiate into many cell types which have wide therapeutic applications.   The dental stem cells are derived from both deciduous and permanent teeth. The viable dental stem cells are very simple to collect, without any mortality and morbidity. Dental pulp stem c...

Transdifferentiation of Human Dental Pulp Stem Cells Into Oligoprogenitor Cells

Introduction: The nerve fibers in central nervous system are surrounded by myelin sheet  which is formed by oligodendrocytes. Cell therapy based on oligodendrocytes and their precursors transplantation can hold a promising alternative treatment for myelin sheet repair in demyelinating diseases. Methods: Human Dental Pulp Stem Cells (hDPSCs) are noninvasive, autologous and easy available s...

Dental Pulp Stem Cells: A Promising Tool for Tissue Regeneration

Stem cells are the “master “ cells of our body that act as building block to regenerate and turn into cells that form tissues, organs and systems in the human body. Several “loci ’’ or “niches” within the adult human body are colonised by a significant number of stem cells. However, access to these potential collection sites often is a limiting point. Growing evidence demonstrates that stem cel...

Different isolation methods of dental pulp stem cells

Considering the ease of isolation and high expansion potential of pulp stem/progenitor cells isolated from wisdom and primary teeth they have been implicated as the most reliable autologous cell source in dental tissue engineering. Meanwhile, different isolation methods have remarkable impacts on the expansion potential of adult stem cells. In enzymatic digestion method extracted teeth as denta...